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![IJMS | Free Full-Text | A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity IJMS | Free Full-Text | A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity](https://pub.mdpi-res.com/ijms/ijms-22-02848/article_deploy/html/images/ijms-22-02848-g003b.png?1615772734)
IJMS | Free Full-Text | A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity
![IJMS | Free Full-Text | A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity IJMS | Free Full-Text | A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity](https://www.mdpi.com/ijms/ijms-22-02848/article_deploy/html/images/ijms-22-02848-g003a.png)
IJMS | Free Full-Text | A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity
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![IJMS | Free Full-Text | A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity IJMS | Free Full-Text | A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity](https://pub.mdpi-res.com/ijms/ijms-22-02848/article_deploy/html/images/ijms-22-02848-ag.png?1615772734)
IJMS | Free Full-Text | A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity
![IJMS | Free Full-Text | A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity IJMS | Free Full-Text | A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity](https://www.mdpi.com/ijms/ijms-22-02848/article_deploy/html/images/ijms-22-02848-g001-550.jpg)